How is Clostridium sordellii treated?

How is Clostridium sordellii treated?

sordellii species are sensitive to penicillins, metronidazole and clindamycin. Treatment should include aggressive therapy for septic shock with volume resuscitation, hemodynamic support with vasopressors if required and early initiation of broad-spectrum antibiotics.

How common is Clostridium sordellii?

Clostridium perfringens is the most common clostridial species (4 to 18 percent of healthy women); C. sordellii is less common (0.5 to 10 percent of healthy women) [8-11].

Can abortion cause toxic shock syndrome?

sordellii toxic shock syndrome and gynecologic infections may be attributed to a rare confluence of events. Pregnancy, childbirth, or abortion may predispose a small number of women to acquire C. sordellii in the vaginal tract, with dilatation of the cervix allowing for ascending infection of necrotic decidual tissue.

What is the mortality rate of C sordellii toxic shock syndrome?

We present a case report of a rare toxic shock syndrome in a post-partum female caused by Clostridium sordellii. Her survival is notable among 16 patients with whom this infection now has a documented 87.5% mortality rate.

How do you get Clostridium sordellii?

Clostridium sordellii infections pose difficult clinical challenges and are usually fatal. Most commonly, these infections occur after trauma, childbirth, and routine gynecological procedures, but they have recently been associated with medically induced abortions and injection drug use.

What bacteria causes toxic shock?

Most commonly, Staphylococcus aureus (staph) bacteria cause toxic shock syndrome. The syndrome can also be caused by group A streptococcus (strep) bacteria.

Is medical abortion life threatening?

The reported frequency of diagnosed and/or treated infection after medical abortion is very low and varies among regimens; it is not life threatening [12].

Can Clostridium perfringens cause sepsis?

perfringens can cause gas gangrene, septic shock, myonecrosis, liver abscess, and hemolysis [1, 2].

How fast does toxic shock happen?

In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in women who are menstruating and using tampons. If you experience the above symptoms after using tampons or after a surgery or skin injury, contact your health care provider immediately.

How do you know if you’re getting toxic shock syndrome?

A sudden high fever. Low blood pressure. Vomiting or diarrhea. A rash resembling a sunburn, particularly on your palms and soles.