What are the clinical manifestations of cherubism?
What are the clinical manifestations of cherubism?
Clinically, cherubism is characterized by bilateral enlargement of the mandible and/or maxilla, causing a rounded face and swollen cheeks accompanied by upward-looking eyes.
What causes cherubism?
Mutations in the SH3BP2 gene have been identified in about 80 percent of people with cherubism. In most of the remaining cases, the genetic cause of the condition is unknown. The SH3BP2 gene provides instructions for making a protein that plays a role in relaying chemical signals within cells.
What is Rainbow syndrome?
Rainbow Syndrome is the second studio album and first major Korean release by South Korean girl group Rainbow. The album was split into two parts, with the first being released on February 13, 2013, containing six songs.
What is the treatment for cherubism?
Treatment of cherubism consists of local curettage of the lesions, jaw contouring, intralesional steroid injections, and systemic calcitonin administration as well. Calcitonin therapy for central giant cell granuloma of the jaws is well documented, and favorable results have been achieved.
What is Mowat Wilson syndrome?
General Discussion. Mowat-Wilson syndrome (MWS) is a rare genetic disorder that may be apparent at birth or later in childhood. MWS is characterized by intellectual disability, distinctive facial features and seizures.
Is there a cure for cherubism?
Is cherubism hereditary?
Cherubism is inherited in an autosomal dominant fashion and is caused by genetic changes in the SH3BP2 gene.
What is Crouzon syndrome?
Crouzon syndrome, also known as craniofacial dysotosis, is a genetic syndrome in which the seams of the skull fuse in abnormally. This affects the shape of the head and face. It is the most common type of syndromic craniosynostosis. Gene mutations are responsible for the abnormal skull fusions.