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What causes acne Conglobata?

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What causes acne Conglobata?

Acne conglobata is believed to be caused by Propionibacterium acnes or P. acnes, the same type of bacteria to blame for regular acne vulgaris. However, to produce this skin condition, this organism causes the body to have a hypersensitive reaction — leading to a chronic inflammatory state.

What is Pash syndrome?

PASH syndrome is a recently identified hereditary autoinflammatory syndrome consisting of multiple neutrophilic dermatoses including pyoderma gangrenosum (PG), acne, and hidradenitis suppurativa (HS). The triad of PG, acne, and HS occurs in extremely rare instances.

What are the 4 grades of acne?

Grades of acne are classified as follows:

  • 7Grade I: The mildest form of acne is referred to as grade I.
  • Grade II: Grade II acne is considered moderate acne.
  • Grade III: Grade III acne is considered moderate to severe acne.
  • Grade IV: Grade IV acne is the most severe grade of acne.

What is similar to hidradenitis suppurativa?

Heart disease. Dissecting cellulitis (severe patchy hair loss on the scalp) Inflammatory bowel diseases (some, like Crohn’s, have skin symptoms that mimic hidradenitis suppurativa) Polycystic ovarian syndrome (hormonal disorder in women)

Can acne conglobata be cured?

Acne conglobata has been successfully treated by carbon dioxide laser combined with topical tretinoin therapy. When severe acne conglobata is unresponsive to more accepted options, modern external beam radiation may be an alternative.

What are tunneling blackheads?

Hidradenitis suppurativa, also known as acne inversa, is a chronic, noncontagious, inflammatory condition characterized by pimple-like bumps or boils and tunnels or tracts on and under the skin.

What is Papash?

PAPASH syndrome is a rare genetic autoinflammatory condition consisting of the following tetrad: pyogenic arthritis, pyoderma gangrenosum (PG), acne vulgaris, and hidradenitis suppurativa (HS). It is thought to be due to a mutation in the PSTPIP1 gene that affects the innate immune system.

What autoimmune disease causes lumps under the skin?

Rheumatoid nodules are firm lumps that develop under the skin. They are fairly unique to rheumatoid arthritis (RA) and usually occur near the affected joints. RA is a long-term progressive autoimmune disease that causes inflammation and pain in and around a person’s joints.