What is a transcriptome of a cell?
What is a transcriptome of a cell?
A transcriptome is a collection of all the gene readouts present in a cell.
What is bacterial transcriptome?
The transcriptome is the comprehensive set of RNAs encoded by an organism’s genome. Metatranscriptomes encompass all RNAs encoded by a group of organisms in a complex sample.
Is transcriptome cell-type specific?
We find evidence that single-cell transcriptome complexity and cell-to-cell variation have cell-type-specific characteristics and that patterns of gene expression variation may be subject to regulation.
How does Single cell transcriptomics work?
Single-cell transcriptomics examines the gene expression level of individual cells in a given population by simultaneously measuring the messenger RNA (mRNA) concentration of hundreds to thousands of genes.
What is the transcriptome and what role does it play in the cell?
A transcriptome represents that small percentage of the genetic code that is transcribed into RNA molecules — estimated to be less than 5% of the genome in humans (Frith et al., 2005). The proportion of transcribed sequences that are non-protein-coding appears to be greater in more complex organisms.
What is transcriptome in molecular biology?
A transcriptome is the full range of messenger RNA, or mRNA, molecules expressed by an organism. The term “transcriptome” can also be used to describe the array of mRNA transcripts produced in a particular cell or tissue type.
What is transcriptomic study?
Transcriptomics is the study of the transcriptome—the complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell—using high-throughput methods, such as microarray analysis.
What is Metatranscriptome sequencing?
What is metatranscriptomic sequencing? Metatranscriptomic sequencing provides direct access to culturable and non-culturable microbial transcriptome information by large-scale, high-throughput sequencing of transcripts from all microbial communities in specific environmental samples.
Why is single cell sequencing important?
Single-cell sequencing technologies can detect individual immune cells, thereby distinguishing different groups of immune cells, as well as discovering new immune cell populations and their relationships (Fig. 2). This helps to understand the complex immune system and propose new targets for disease treatment.
What is transcriptomics used for?
Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription.
What is transcriptome study?
Transcriptome Analysis is the study of the transcriptome, of the complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell, using high-throughput methods.
Why is the transcriptome important?
Understanding the transcriptome is essential for interpreting the functional elements of the genome and revealing the molecular constituents of cells and tissues, and also for understanding development and disease.