What is c-fos immunohistochemistry?
What is c-fos immunohistochemistry?
C-fos is a proto-oncogene that is expressed within some neurons following depolarization. The protein product, c-fos protein, can be identified by immunohistochemical techniques. Therefore, c-fos expression might be used as a marker for neuronal activity throughout the neuraxis following peripheral stimulation.
What is Cfos stain?
c-Fos is an immediate early gene (IEG) that codes for a transcription factor that is thought to mediate long-term changes in neural functioning.
What is the function of c-fos?
c-Fos is currently used as a marker of neuronal activity and has been associated with a number of neural and behavioral responses to acute stimuli expression.
Is c-fos a transcription factor?
Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. It is encoded in humans by the FOS gene….Protein c-Fos.
| RNA expression pattern | |
|---|---|
| BioGPS | More reference expression data |
What is optogenetics technology?
In 2005, a new technique was created, called optogenetics. This technique uses a combination of light and genetic engineering (changing the genetic information of a living thing by inserting or deleting information in the genetic code) to control the cells of the brain.
Why are immediate early genes important?
Immediate-early genes have important roles in processes such as brain development, learning, and responses to drug abuse. Further, immediate-early genes play an essential role in cellular responses that contribute to long-term neuronal plasticity.
What is cFosSpeed service?
cFosSpeed is traffic shaping software often bundled with MSI motherboards for the Windows operating system. The program attaches itself as a device driver to the Windows network stack where it performs packet inspection and layer-7 protocol analysis.
Why is blue light used in optogenetics?
Blue light has minimal effects on resting microglia that have not been exposed to LPS. The researchers suspect that the light triggers a cascade of signals in activated microglia that dampen the expression of NF-kappaB — a transcription factor that regulates other inflammatory genes.
What does the optogenetic technique enable researchers to test?
Optogenetics unlocks the ability to activate or inhibit select populations of neurons. With this technique, researchers have been able to investigate the causal relationship between neural activity, function, and behaviour.
Is c-fos an immediate early gene?
The expression of Immediate Early Genes (IEGs) such as, c-fos, Egr1 and arc are selectively and promptly upregulated in learning and memory among neuronal subpopulations in regions associated with these processes.
What is FOS neuroscience?
The detection of the Fos protein, a product of the cfos gene, within neurons is a common procedure used in behavioral neuroscience research to identify neurons and circuits within the brain that are active during certain behavioral situations.