What is Ocusert?
What is Ocusert?
➢Ocular insert (Ocusert) are sterile preparation that. prolong residence time of drug with a controlled release manner and negligible or less affected by nasolacrimal drainage. ➢It shows diffusion controlled release. ➢It consists of a central reservoir of drug enclosed in. specially designed microporous membrane …
Which type of drug delivery system Ocusert is?
Ocuserts system is a novel drug delivery system is based on porous membrane. The release of drug from diffusional inserts/ocuserts is based on a diffusional release mechanism.
What is ophthalmic insert?
Ocular inserts are defined as sterile, thin, multilayered, drug-impregnated, solid or semisolid consistency devices placed into the cul-de-sac or conjuctival sac, whose size and shape are especially designed for ophthalmic application. They are composed of a polymeric support that may or may not contain a drug.
Which of the following is a known erodible insert?
The marketed devices of erodible drug inserts are Lacriserts, SODI, and Minidisc.
What is Ocusert example?
A brand name for a device that leaches PILOCARPINE into the conjunctival sac, for the treatment of GLAUCOMA.
Which of the following drug is incorporated into the Ocusert implant?
Related to cul-de-sac inserts, we can mention Ocusert, which provides sustained release for the ocular hypotensive drug pilocarpine. It is made of two outer layers of ethylene–vinyl acetate copolymer (EVA) and an inner layer of pilocarpine in an alginate gel within di(ethylhexyl) phthalate [473].
What is colon targeted drug delivery system?
Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer.
What is ocular drug delivery system?
Ocular drug delivery system (ODDS) is a dosage form, vehicle, or system intended for instilling, administering, or delivering drug/medicine to eye against any ailment or disorder involving or affecting vision. It ranges from simple sterile eye drop for the ocular surface to complex implants for intraocular tissue.
What is ocular drug delivery?
What circumstances should the product Ocusert Pilo be used?
What Conditions does PILOCARPINE HCL Treat?
- increased pressure in the eye.
- wide-angle glaucoma.
- acute angle-closure glaucoma.
- decreasing pupil size during eye surgery.
What are the 4 drug delivery methods?
Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles, cargo, and targeting strategies. Medications can be taken in a variety of ways—by swallowing, by inhalation, by absorption through the skin, or by intravenous injection.
What are ophthalmic medications?
Ophthalmic anti-infectives are anti-infectives contained in a product formulated especially to be instilled or applied in the eye or eyes. Ophthalmic anti-infectives include eyedrops, gels or ointments. Anti-infectives are drugs that can either kill an infectious agent or inhibit it from spreading.
What does ALZA Corporation do?
As one of the world’s leading producers of drug delivery systems, ALZA Corporation develops and manufactures a variety of systems that make administration of medication more efficient and effective. The systems ALZA develops are used by other pharmaceutical companies as well as by ALZA itself for its own drug portfolio.
When did Alza start making products?
The company had its first profitable year in 1983 and was listed on the American Stock Exchange. The following year, ALZA purchased land in Vacaville, California, to build a 117,000-square-foot commercial manufacturing facility. The Vacaville facility became the center for the manufacture of several transdermal and oral products.
What is Ocusert® pilocarpine ocular therapeutic system?
Ocusert®, pilocarpine ocular therapeutic system is the first product marketed by Alza Corporation. Glaucoma is a group of disease of the eye…
How much did Alza buy sequus for?
Grzanka, Len, ‘Drug Company Patches In to Growing World Market,’ San Francisco Business Times, June 11, 1999, p. S6. King, Ralph T., Jr., ‘ALZA Corp. Agrees to Purchase Sequus for $580 Million,’ Wall Street Journal, October 6, 1998, p.